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SUNY Downstate Medical Center Pediatric Faculty Research Publications & Grants (2001-2007) Glibetic M, Samlalsingh-Parker J, Raykova V, Ofenstein J, Aranda JV. Group B Streptococci and inducible nitric oxide synthase: modulation by nuclear factor kappa B and ibuprofen. Semin Perinatol. 2001 Apr; 25(2):65-9. Raykova VD, Glibetic M, Ofenstein JP, and Aranda JV. Nitric oxide-dependent regulation of pro-inflammatory cytokines in Group B Streptococcal rat lung inflammation. Ann Clin Lab Sci. 2003; 33:62-7. Ergun H, Frattarelli DA, Aranda JV: Characterization of the role of physiochemical factors on the hydrolysis of dipyrone. J Pharm Biomed Anal. 2004 May 28;35(3):479-87. Kapur G, Mattoo T, Aranda JV. Pharmacogenomics and renal drug handling in newborns. Sem Perinatol. 2004.:28:132-140. Prescilla RP, Frattarelli DA, Haritos D, Aranda JV, Edwards DJ: Pharmacokinetics of Rofecoxib in Children With Sickle Cell Hemoglobinopathy. J Pediatr Hematol Oncol. 4004 Oct:26(10):661-664. Sood BG, Delaney-Black V, Aranda JV, Shankaran S: Aerosolized PGE1: A selective Pulmonary Vasodilator in Neonatal Hypoxemic Respiratory Failure Results of a Phase I/II Open Label Clinical Trial. Pediatr Res. 4004 Oct;56(4):579-85. Epub 2004 Aug 04. VanWoerkom R, Beharry K DA, Modanlou H, Parker J, Rajan V, Akmal Y, Aranda JV. Influence of morphine and Naloxone on endothelin and its receptors in newborn piglet brain vascular endothelial cells: clinical implications in neonatal care. Pediatric Research 2004: 55: 147-151. Jacobs RF, Maples HD, Aranda JV, Espinoza GM, Knirsch C, Chandra R, Fisher JM, Kearns GL. Pharmacokinetics of Intravenously Administered Azithromycin in Pediatric Patients. J Pediatr Infect Dis J. 2005 Jan:24(3):34-9 Thomas RL, Parker GC, Van Overmeire B, Aranda JV. A meta-analysis of ibuprofen versus indomethacin for closure of patent ductus arteriosus.Eur J Pediatr. 2005 Mar;164(3):135-40. Epub 2004 Dec 10. Edwards DJ, Chugani DC, Chugani HT, Chehab J, Malian M, Aranda JV. Pharmacokinetics of Buspirone in autistic children. J Clin Pharmacol. 2006 May;46(5):508-14. Aranda JV, Carlo W, Hummel P, Thomas R, Lehr VT, Anand KJ.; Analgesia and sedation during mechanical ventilation in neonates Clin Ther. 2005 Jun;27(6):877- 899. Beharry KD, Modanlou HD, Hasan J, GHarraee Z, Abad-Santos P, Sills JH, Jan A, Nageotte S, Aranda JV. Comparative Effects of Early Postnatal Ibuprofen and Indomethacin on VEGF, IGF-I, and GH during Rat Ocular Development. Investigative Opthalmology & Visual Scince, 2006, Jul;47(7):3036-43. Ongoing Research Support 5-U01HD-37261-01 (PI: J. V. Aranda, MD, PhD) $1,984,324.00 1/1/2004– 12/31/2008 30% NICHD Children’s Center for Clinical Pharmacology Research-Pediatric Pharmacology Research Unit Network (PPRU) Competing Renewal 3U01HD-37261-04S1 Aranda (PI) $ 200,000.00 9/2002-8/2003 (extended-2006) NIH Targeted Drug Delivery Using Novel Polymeric Nanostructures, Applications in Asthma and Thrombolysis. Supplemental funding from the NICHD: 1) to study the effects of dendrimer-methylprednisolone complex delivered by aerosol in a mouse model of asthma, 2) to study the ability of antifibrin antibody-dendrimer-tissue plasminogen activator complex to dissolve clots induced in the internal jugular vein of rabbits. Project PI: M. Lieh Lai 3U01HD-37261-04S2 Aranda (PI) (200,000.00 9/2002-8/2003(extended 2006) NIH Early Pharmacotherapy Aimed at Neuroplasticity in Autism. Supplemental funding from the NICHD: 1) to determine the pharmacokinetic profile of Buspirone in young children, 2) to determine efficacy, safety and population PK of Buspirone in autistic children and 3) to determine the role of genetic polymorphism in drug response. Project PI: D. Chugani WOMC- 2005 Ontogeny of GABA receptors in Newborn Infants with Apnea ;PI: J. V. Aranda 1/1/2005- 12/31/2007 effort=10 % Role: Principal Investigator – J. V. Aranda Gerber Foundation ( $ 165,000.00) 7/01/2007-7/01/2009 Adverse Drug Reaction Diagnostic Tool for the Newborn . Du, W- (PI) and J.V. Aranda, Co PI NIH - 1R03 HD057566-01 (Aranda JV- PI) (pending) 01/01/2008-01/01/2010 Absorption and Metabolism of Oral Codeine in Mechanically Ventilated Neonates 583E-URO-0581-006 Aranda (PI) 6/19/02-6/30/04 Pharmacia & Upjohn Company An Open Label, Phase III, 12 Month Study of the Long-Term Clinical Efficacy, Safety and Tolerability of Tolterodine Oral Solution and PR Capsules in Children with Detrusor Hyperreflexia Ages 4 Months to 16 Years of Age. Role: PI FCR-00-01/Ross CB Aranda (PI) 5/10/02-5/9/05 Farmacon, IL-LLC A Randomized Double Blind Study of Ibuprofen L-Lysinate Intravenous Solution in Premature Infants for the Early Treatment of PDA. Role: PI A06610491001 Aranda (PI) 3/20/02-3/31/03 Pfizer, Inc. An Open-Label Evaluation of the Pharmacokinetics and Safety of a Single 10mg/kg Dose of Intravenously Administered Azithromycin in Hospital Children. Role: PI C-2000-042/20012372 Aranda (PI) 8/28/01-9/30/03 Alza Corporation The Safety and Tolerability of Ocybutynin Chloride (Ditropan XL, Ditropan Syrup or Ditropan Tablets) in the Treatment of Detrusor Hyperreflexia Due to Neurogenic Conditions in Children). Role: PI B4Z-MC-LYAI Aranda (PI) 6/13/01-6/30/03 Eli Lilly and Company, Lilly Research Laboratories Long Term, Open-Label, Safety Study of Tomoxetine HCl in Patients, 6 Years and Older. Role: PI99-0-063 Aranda (PI) 7/1/00-6/30/03Fujisawa Healthcare, Inc. Pharmacokinetic, Safety and Tolerance Study of Three Doses of FK463 in Premature Infants.Role: PI PENDING RESEARCH SUPPORT NIH-NIEHS: RO1: Lead I n the pathogenesis of Pediatric Diabetes: Biomarkers, mechanisms and Therapy. $ 11,985,253.00- total cost ( 07/01/2007 to 06/30/2012 -) PIs: Novak R and Aranda JV NIH: RO3: A multicenter Clinical Trial on the absorption and Metabolism of oral codeine in Mechanically ventrilated newborns. $ 195, 091.00 Total cost ( 12-01-2007 to 11-30-2009) PI: Aranda JV and the PPRU Network Completed Research Support 1-U01HD-37261 Aranda (PI) 1999-2004 NICHD Children’s Center for Clinical Pharmacology Studies. The major goals of this project are to conduct studies on the metabolism and disposition of drugs in the pediatric population in order to provide improved guidelines and labeling of drugs for use in children.
583E-URO-0581-001 Aranda (PI) 9/11/01-3/20/02 Pharmacia & Upjohn Company Phase I/II, Open Label, Dose-Escalating Pharmacokinetic, Pharmacodynamic (Urodynamic) and Clinical Effect, and Safety Study of Tolterodine PR Capsules in Children with Detrusor Hyperreflexia 1 Month to 4 Years of Age.
583E-URO-0581-002 Aranda (PI) 9/11/01-3/20/02 Pharmacia & Upjohn Company Phase I/II, Open Label, Dose-Escalating Pharmacokinetic, Pharmacodynamic (Urodynamic) and Clinical Effect, and Safety Study of Tolterodine PR Capsules in Children with Detrusor Hyperreflexia 5 to 10 Years of Age.
583E-URO-0581-003 Aranda (PI) 9/11/01-3/20/02 Pharmacia & Upjohn Company Phase I/II, Open Label, Dose-Escalating Pharmacokinetic, Pharmacodynamic (Urodynamic) and Clinical Effect, and Safety Study of Tolterodine PR Capsules in Children with Detrusor Hyperreflexia 11 to 15 Years of Age.
B4Z-MC-LYAQ Aranda (PI) 1/11/01-1/31/03 Lilly Research Laboratories Safety and Efficacy of Tomoxetine or Tomoxetine Plus Fluosetine in the Treatment of Mixed Attentional and Affective Disorders.
PO1392-65 Aranda (PI) 8/10/00-8/9/02 Schering Plough Research Institute A Phase IV Multicenter, Randomized, Parallel Group, Safety Study in Pediatric Subjects with Atopic Dermatitis Treated Once Daily for Three Weeks with Elocon Cream, Elocon Ointment or Elocon Lotion.
S3B30015 Aranda (PI) 2/10/00-4/30/01 ICON Clinical Research An Eight-Week, Randomized, Double-Blind, Placebo-Controlled Study of Alosetron in Non-Constipated Adolescents with Irritable Bowel Syndrome.
S3B30019 Aranda (PI) 2/10/00-4/30/01 ICON Clinical Research A Sixteen-Week, Open-Label, Safety Study of Alosetron in Non-Constipated Adolescents with Irritable Bowel Syndrome.
FEN-USA-87 Aranda (PI) 11/16/99-11/16/02 Janssen Pharmaceuticals, L.P. A Study to Assess the Safety, dose Conversion, and Titration of Duragesic (Fentanyl Transdermal System) in Pediatric Patients with Chronic Pain Requiring Opioid Therapy.
Sternberg A, Murphy C, Austin-Leon G, Rao M, Application of shotokan karate exercises in an obese inner-city pediatric population who participated in the Downstart healthy lifestyle program. Med Sci Sports Exerc. 2007 May:39(5Suppl):S387
Principal Investigator, Jeffrey Birnbaum, Ryan White Title IV/Health Resources and Services Administration, US Department of Health and Human Services “Coordinated HIV Services and Access to Research for Women, Infants, Children and their Families Initiative”. 2006-present Principal Investigator, Jeffery Birnbaum, Ryan White Title IV/Health Resources and Services Administration, US Department of Health and Human Services “Youth Services Initiative”. 2001-present Principal Investigator, Jeffrey Birnbaum, “Specialized Care Center for HIV Positive Adolescents”, AIDS Institute, Department of Health, State of New York. 2000- present Principal Investigator, Jeffrey Birnbaum, Longitudinal Epidemiologic Study to Gain Insight into HIV and AIDS in Children and Youth (LEGACY), Centers for Disease Control and Prevention, Atlanta, GA/WERSTAT 2005-present Principal Investigator, Jeffrey Birnbaum, “HIV Planning Grant”, Ryan White Title III/Health Resources and Services Administration, US Dep’t of Health and Human Services 2003-2002 Principal Investigator, Jeffrey Birnbaum, “Natural History of HIV disease specific to an Adolescent Population, Adolescent Medicine HIV and AIDS Research Network, national Institutes of Health. 2001-1997 “Adolescent Medicine HIV and AIDS Research Network”: Jeffrey Birnbaum, Study of natural history of HIV disease specific to an adolescent population; National Institute of Child Health and Human Development. 1997-2001 Eastwood EA, Birnbaum JM. Physical and Sexual Abuse and Unstable Housing among Adolescents with HIV. AIDS & Behavior. 2007 (currently in press, accepted lst draft March 2007) Rotheram-Borus MJ, Lee MB, Murphy DA, Futterman D, Duan N, Birnbaum JM, Lightfoot M. Efficacy of a Preventative Intervention for Youths Living with HIV. Am J Public Health. 2001 March;91 (3):400-5. Rotheram-Borus MJ, Lee M, Zhou S, O’Hara P, Birnbaum JM, Swendeman D, et al. Variation in health and risk behavior among youth living with HIV. AIDS Educ Prev 2001 Feb;13(1):42-54. Principal Investigator, S.W. Blain, PhD, American Cancer Society Research Scholar Award, p27Kip1 and cyclin D-cdk4:Cell cycle dependent Inhibition or Activation?, 7/106-6/31/10 Principal Investigator, S.W. Blain, PhD, Dean’s Research Initiative pilot Project Award: Are the catalytic and Sequestration Functions of Cyclin D-cdk4 Required Equally? 2/2004-1/31-2005 Principal Investigator, S.W. Blain, PhD, Alzheimer’s Association New Investigator Award, The role of cdk4 and p27Kip1, in Neuronal Cell Death, 7/1/07-6/31/09 Principal Investigator, S.W. Blain, PhD, NIH RO1, A TGF-B Responsive Gene Therapy Vector that Kills Metastatic Breast Cancer, 9/30/07-8/31/12 Principal Investigator, S.W. Blain, PhD Susan G, Komen Breast Cancer Foundation, A TGF-B-Responsive Gene Vector (TRGT) that Kills Metastactic Breast Cancer, 6/05-4/07
Gundogan, NU, Castells, S: Thyroid Function Tests and Hypothacnic-pituitary-adrenal Axis in Infantile Austism: Some Basis Endocrine4 Topics of Debate. Ann. Med. Sci. 1:2-7, 2001. Taha, D, Bastian, W. Castells, S: Growth Hormone Replacement Therapy in Children with Leukemia in Remission. Clin. Pediatr. 40:441-445, 2001. Umpaichitra, V. Bastian, W,Castells, S:Hypocalcemia in Children: Pathogenesis and Management. Clin. Pediatr. 40:305-312,2001. Umpaichitra, V. Bastian, W, Taha, D,Bannerji, MA, Castells, S: C-peptide and Glucagon Profiles in Minority Children with Type 2 Diabetes Mellitus. J. Clin. Endocrinol. Metab. 86:1605-1609, 2001. Taha, D, Castells, S. Umpaichitra, V, Bastian, W,Bannerji, MA, Beta Cell Response to Intravenous Glucagon Stimulation with Type 2 Diabetes Mellitus. J. Clin Endocrinol. Metab.86:1605-1609, 2001. Umpaichitra, V, Wallerstein, R. Castells, S: Dyplasia with Abnormal Urinary Glycosaminoglycans and Growth Hormone Unresponsiveness. Clinical Dysmorphology, 11:53-56, 2002. Umpaichitra, V, Banerji, MA, Castells, S: Autoantibodies in Children with Type 2 Diabetes. J. Pediatr. Endocr. Metab. 15:525-530, 2002. Castells, S: Management of Hyperglycemia in Minority Children with Type 2 Diabetes Mellitus. J. Pediatr. Endo. Metab. 15:531-540, 2002. Taha, D., Umpaichitra, V, Banerji, M.A., Castells, S. Type 2 Diabetes Mellitus in African-American Adolescents: Impaired Beta-Cell Function in the face of server Insulin Resistance J. Pediatri Endocr Metab 19:135-142, 2006 Mahesh, S. Karp, R. Castells, S, Quintos, J.B. Mauriac Sydrome in a 3 year old boy. Endocrine Practice 13:63-66, 2007. Mercado, A. B. Castells, S.: Pancreatic B-Cell Hyperactivity in Morbid Obese Adolescent Pediatr. Endocr. Reviews, 3, Supplement 4: 560-563, 2006 Quintos, J.B., Castells S:, Management of Metabolic Syndrome in Morbidly Obese Children and Adolescents. Pediatr. Endocr. Review 3:4:564-570, 2006 Quintos, JB, Mazumdar, H, George M, Mercado, AB, Lu, Haiyan, Sternberg, A, Rao, M., Castells, S,: The Prevalance of Metabolic syndrome in Inner City Obese African-American Youth. Pediatr. Endocr. Review 3; Supplement 4: 571-575, 2006. Quintos,JB, Shak, A. Castells, S, Transient Pitutiary Dysfunction, Empty Sella, Pseudotumor Cerebri in a Morbid Obese Adolescent, Pediatr. Endocr. Review 3; Supplement 4:576-578, 2006 Mahesh S, Karp RJ, Castells S, Quintos JB. Mauriac syndrome in a 3 year old boy. Endocr Pract.2007 Jan-Feb;13(1):63-6.
Resident and Faculty Perceptions of Structured Clinical Observations in a Pediatric Continuity Clinic: Laura Dattner, MD Dattner L, Ozuah PO. Career Decision-Making among Pediatric Residents. Medical Education Online. 2005;10:18. Dattner L , Fordjour L, Wadowski S. Competency Goals of Incoming Pediatric Residents. Presented at the Pediatric Academic Society Annual Meeting, Toronto, Canada, May 2007. Publication 7908.12A. Adverse Neonatal Outcomes of large Gestnal Age Neonates Associated with Maternal Obesity in a Predominantly African and Caribbean American Inner City Population: Lawrence K. Fordjour MD, James Choi, John Kral, MD, Laura Dattner, MD, Gloria Valencia, MD and Magdy El-Hennawy, MD Precepting in a Pediatric Resident Continuity Clinic: Laura Dattner
Seeyave D, Desai N, Miller ST, Rao SP, Piecuch S. Fatal delayed transfusion reaction in a sickle cell anemia patient with Serratia marcescens sepsis. Natl Med Assoc. 2006;98: 1697-1699. Mathur M, Desai N, Sharma J, Rao SP, Goldman GM, Management of a large intraatrial catheter-tip thrombus in a child with acquired immunodeficiency syndrome using escalating tissue plasminogen activator infusions. Pediatr Crit Care Med. 2005; 6:79-82. Desai N, Mathur M, Abu-Lawi K, HIV-1 seronegativity in a child with proved Perinatal HIV infection on HAART – Sex Transm Infect 2005:81:377-379 doi:10.1136/sti.2004.011973
Dinkevich E, Cunningham SJ, Crain EF. Parental Perceptions of Access to Care for Inner-City Children with Asthma. Journal of Asthma. 1998:35:63-71. Dinkevich E. Ozuah PO. Pyloric stenosis. Pediatrics in Review. 2000:21:249-50 Ozuah PO, Curtis J, Dinkevich E. Physical examination skills of US and international medical graduates. JAMA, 2001;286:1021. Dinkevich E, Hupert J, Moyer V. Evidence-Based Well-Care. BMJ. 2001:323:646-649. Dinkevich E, Ozuah P, Well-child Care: Effectiveness of Current Recommendations, Clinical Pediatrics, 2002;41(4):211-217. Dinkevich E, Ozuah P, Self-Directed Learning Activities of Pediatric Residents. Medical Education, 2003;37:388-389. Dinkevich E, Markinson A, Ahsan S, Lawrence B, Effect of a Brief Intervention on Evidence-Based Medicine Skills of Pediatric Residents. Submitted for publication. Divald A, Karl PI,
Fisher SE: Regulation of Phospholipase D in human placental trophoblasts by P2 purinergic receptors, Placenta, 23:584-593, 2002 Isenovic ER, Divald A, Milivojevic N, Grgurevic T, Fisher SE, Sowers JR: Interactive effects of insulin-like growth factor-1 and beta-estradiol on endothelial nitric oxide synthase activity in rat aortic endothelial cells. Metabolism, 52: 482-7, 2003
Fordjour L ., Choi J., Kral J., Dattner L., Valencia G. and El-Hennawy M. Adverse Neonatal Outcomes of Large for Gestational Age Neonates Associated with Maternal Obesity in a Predominantly African- and Caribbean-American Inner-City Population , Pediatric Academic Society, Toronto, 2007. Publication 7924.1 Margaret Clark Golden Video: approach to the Pediatric Exam, Exam of the Newborn, and Exam of the Toddler in Swartz, Mark, Textbook of Physical Diagnosis, 5th Edition. Saunders PA 2006. Principal Investigator, Margaret Clark Golden, OrthoMcNeil, Surveillance of fecal carriage of extended Spectrum B-lactamase-producing Gram-negative Enterobacteriaceae in healthy newborns, infants and hospitalized neonates. 6/07-5/08.
Principal Investigator, Hammerschlag MR, Pfizer, In vitro Activity of New Pfizer Compounds Against Chlamydia pneumoniae. 7/07-6/08. Principal Investigator, Kumar Swati, mentor, Hammerschlag, MR Medlmunne Pediatric ID Fellowship Grant, Effects of Smoking on the Burden of Chlamydia pneumoniae Infection in the Lung and its Systemic Dissemination in Mice. 7/05-6/08 Principal Investigator, Hammerschlag MR, Focus Diagnostics, Inc. Retrospective analysis of previously cultured clinical specimens for Chlamydia pneumoniae by Focus Nucleic Acid Amplification Test, 7/07-12/07.Boman J, Roblin PM, Sundström P, Sandström M, Hammerschlag MR. Failure to detect Chlamydia pneumoniae in the central nervous system of patients with multiple sclerosis. Neurology 54:265, 2000. Hammerschlag MR. Chlamydia pneumoniae and atherosclerosis: what we know and what we don't know. Pediatr Infect Dis J 19:75-76, 2000. Hammerschlag MR. Activity of gemifloxacin and other new quinolones against Chlamydia pneumoniae: a review. J Antimicrob Chemother 45: Suppl S1:35-39, 2000. Hammerschlag MR. The role of Chlamydia in upper respiratory tract infections. Curr Infect Dis Rep 2:115-120, 2000. Suss AL, Homel P, Hammerschlag M, Bromberg K. Risk factors for pelvic inflammatory disease in inner-city adolescents. Sex Transm Dis 27:289-91, 2000. Strigl S, Roblin PM, Reznik T, Hammerschlag MR. In vitro activity of ABT 773, a new ketolide antibiotic, against Chlamydia pneumoniae. Antimicrob Agents Chemother 44:1112-1113, 2000. Strigl S, Kutlin A, Roblin PM, Shulman ST, Hammmerschlag MR. Is there an association between Kawasaki Disease and Chlamydia pneumoniae? J Infect Dis 181:2103-5, 2000. Hammerschlag MR, Roblin PM. Microbiologic efficacy of levofloxacin for the treatment of community-acquired pneumonia due to Chlamydia pneumoniae. Antimicrob Agents Chemother 44:1409, 2000. Hammerschlag MR, Roblin PM. Microbiologic efficacy of moxifloxacin for the treatment of community-acquired pneumonia due to Chlamydia pneumoniae. Int J Antimicrob Agents 15:149-152, 2000. Roblin PM, Hammerschlag MR. In vitro activity of GAR-936 against Chlamydia pneumoniae and Chlamydia trachomatis. Int J Antimicrob Agents 16:61-63, 2000. Ke Z, Lu F, Roblin P, Boman J, Hammerschlag MR, Kalman B. Is Chlamydia pneumoniae present in brain lesions of patients with multiple sclerosis? J Clin Microbiol 38:4274-6, 2000. Hammerschlag MR. Chlamydia pneumoniae and the lung. Eur Resp J 16:1001-7, 2000. Hammerschlag MR, Boman J, Rowley AH. Failure to demonstrate Chlamydia pneumoniae in cardiovascular tissue from children with Kawasaki Disease. Pediatr Infect Dis J 20: 76-77, 2001. Dowell SF, Peeling RW, Boman J, Carlone GM, Fields BS, Guarner J, Hammerschlag MR, Jackson LA, Kuo CC, Maass M, Messmer TO, Talkington DF, Tondella ML, Zaki SR. Standardizing Chlamydia pneumoniae assays: Recommendations from the Centers for Disease Control and Prevention (USA) and the Laboratory Centre for Disease Control (Canada). Clin Infect Dis 33:492-503, 2001. Hammerschlag MR. Mycoplasma pneumoniae infections. Curr Op Infect Dis, 14:181-6, 2001. Hammerschlag MR. Use of nucleic acid amplification tests in investigating child sexual abuse. Sex Transm Infect, 77:153-4, 2001. Hammerschlag MR. Current status of laboratory diagnosis of Chlamydia pneumoniae and Chlamydia psittaci. Clin Microbiol Newsl 23:107-111, 2001. Hammerschlag MR. Asymptomatic respiratory infection with Chlamydia pneumoniae: What does it mean? Chest 119:1303-5, 2001. Reiss AB, Awadallah NW, Roblin PM, Chan ESL, Montesinos MC, Khoa ND, Cronstein BN, Hammerschlag MR. Immune modulation of cholesterol homeostasis. Recent Res Devel Protein Eng 1:21-38, 2001 Kutlin A, Flegg C, Stenzel D, Reznik T, Roblin PM, Mathews S, Timms P, Hammerschlag MR. Ultrastructural study of Chlamydia pneumoniae in a continuous infection model. J Clin Microbiol 39:3721-3, 2001.Hammerschlag MR, Roblin PM, Bébéar CM. Activity of telithromycin, a new ketolide antimicrobial, against atypical and intracellular respiratory tract pathogens. J Antimicrob Chemother, 48:Topic T1, 25-31, 2001. Boman J, Hammerschlag MR. Chlamydia pneumoniae and atherosclerosis - a critical assessment of diagnostic methods and the relevance to treatment studies. Clin Microbiol Rev 15:1-20, 2002 Kutlin A, Roblin PM, Hammerschlag MR. Effect of prolonged treatment with azithromycin, clarithromycin and levofloxacin on Chlamydia pneumoniae in a continuous infection model. Antimicrob Agents Chemother 46:409-412, 2002. Malay S, Roblin PM, Reznik T, Kutlin A, Hammerschlag MR. In vitro activity of BMS-28476 against Chlamydia trachomatis and recent clinical isolates of Chlamydia pneumoniae. Atimicrob Agents Chemother 46:517-518, 2002. Kutlin A, Roblin PM, Hammerschlag MR. Effect of gemifloxacin on viability of Chlamydia pneumoniae (Chlamydophila pneumoniae) in an in vitro continuous infection model. J Antimicrob Chemother 49:763-767, 2002. Chernesky M, Smieja M, Schachter J, Summersgill J, Schindler L, Solomon N, Campbell K, Campbell LA, Cappuccio A, Gaydos C, Chong S, Moncada J, Phillips J, Jang D, Wood BJ, Petrich A, Hammerschlag MR,Cerney M, Mahony J. Comparison of an industry derived LCx® Chlamydia pneumoniae PCR research kit to in-house assays performed in five laboratories. J Clin Microbiol 40: 2357-2362, 2002. Hammerschlag MR. Chlamydia pneumoniae and the heart: Impact of diagnostic methods. Curr Clin Topics Infect Dis 22:24-41, 2002 Hammerschlag MR. Intracellular life of Chlamydiae. Sem Pediatr Infect Dis 4:239-248, 2002. Hammerschlag MR. Community-acquired MRSA infections: A new twist for an old bug. Infect Med 20:8-9, 2003. Hammerschlag MR. Implications of inappropriate STD testing go beyond pure diagnostics. ASM News 69:74-79, 2003. Roblin PM, Reznik T, Kutlin A, Hammerschlag MR. In vitro activity of rifamycin derivatives ABI-1648 (Rifalazil, KRM-1648), ABI-1657 and ABI-1131 against Chlamydia trachomatis and recent clinical isolates of Chlamydia pneumoniae. Antimicrob Agents Chemother 47:1135-1136, 2003. Hogan R, Mathews S, Kutlin A, Hammerschlag MR Timms P. Differential expression of genes encoding membrane proteins between acute and continuous Chlamydia pneumoniae infections. Microb Pathogen 34:11-16, 2003. Roblin PM, Reznik T, Hammerschlag MR. In vitro activity of a novel new antibiotic, NVP-PDF386, against Chlamydia pneumoniae. Antimicrob Agents Chemother 47:1447-1448, 2003. Hammerschlag MR, Reznik T, Roblin PM, Summersgill J, Bukofzer S. Microbiologic efficacy of ABT-773 (cethromycin) for treatment of community acquired pneumonia due to Chlamydia pneumoniae. J Antimicrob Chemother 51:1025-1028, 2003. Hammerschlag MR. Pneumonia due to Chlamydia pneumoniae in children: Epidemiology, diagnosis and treatment. Pediatr Pulmonol 36:384-390, 2003. Cultrara A, Goldstein N, Ovchinsky A, Reznik T, Roblin PM, Hammerschlag MR. The role of Chlamydia pneumoniae in children with chronic sinusitis. Arch Otolaryngol 129:1094-1097, 2003. Hammerschlag MR. Appropriate use of nonculture tests for the detection of sexually transmitted diseases in children and adolescents. Sem Pediatr Infect Dis 14:54-59, 2003. Roblin PM, Reznik T, Hammerschlag MR In vitro activity of garenoxacin against recent clinical isolates of Chlamydia pneumoniae. Int J Antimicrob Agents 21:578-580, 2003. Kohlhoff SA, Hammerschlag MR. Raccoon roundworm (Baylisascaris procyonis). Infect Med 20:218-223, 2003. Hammerschlag MR. West Nile Virus: from epidemic to endemic. Infect Med 20:374-5, 2003. Hammerschlag MR. Advances in the management of Chlamydia pneumoniae infections. Expert Rev Anti-Infect Ther 1:493-504, 2003.Hammerschlag MR. Infections due to Chlamydia trachomatis and Chlamydia pneumoniae in children and adolescents. Pediatr Rev 25:43-50, 2004. Ramilo PB, Augenbraun M, Hammerschlag MR. Recent outbreaks on cruise ships. Infect Med, 21:14-15, 2004. Hammerschlag MR. Clinical advances in the treatment of Chlamydia pneumoniae infections. Mod Aspects Immunobiol, in press, 2004. Goyal M, Miller ST, Hammerschlag MR, Gelling M, Gaydos CA, Hardick J, Wood BJ, Reznik T, Rao SP. Is Chlamydia pneumoniae infection associated with stroke in children with sickle cell disease? Pediatrics,113:e318-e321, 2004. URL:http://www.pediatrics.org/cgi/content/full/4/e318 Kohlhoff SA, Roblin PM, Reznik T, Hawser S, Islam K, Hammerschlag MR. In vitro activity of a novel diaminopyrimidine compound, iclaprim, against Chlamydia trachomatis and C. pneumoniae. Antimicob Agents Chemother, 48:1885-6, 2004. Kumar S, Hammerschlag MR. The accidental tourist: Globalization and food-borne disease outbreaks. Infect Med 21:149-51, 2004. Hammerschlag MR, Roblin PM. The in vitro activity of a new fluroquinolone, ABT-492, against recent clinical isolates of Chlamydia pneumoniae. J Antimicrob Chemother 54:281-2, 2004. Riska PF, Kutlin A, Ajiboye P, Cua A, Roblin PM, Hammerschlag MR. Genetic and culture-based approaches for detecting microcline resistance in Chlamydia pneumoniae. Antimicrob Agents Chemother 48:3586-3690, 2004. Alam M, Hammerschlag MR. SARS and emerging zoonoses. Infect Med 21:327-328,2004. Kutlin A, Kohlhoff S, Roblin P, Hammerschlag MR, Riska P. Emergence of resistance to rifampin and rifalazil in Chlamydophila pneumoniae and Chlamydia trachomatis. Antimicrob Agents Chemother 49:903-907, 2005. Pelton SI, Hammerschlag MR, Overcoming current obstacles in the management of bacterial community acquired pneumonia in ambulatory children. Clin Pediatr 44:1-17, 2005. Hashimi N, Hammerschlag MR. Human metapneumovirus. Infect Med 22: 21-22, 2005. Senn L, Hammerschlag MR, Greub G. Therapeutic approaches to Chlamydia infections. Expert Opinion Pharmacother 6:1-10, 2005. Kumar S, Kohlhoff S, Gelling M, Roblin PM, Kutlin A, Kahane S, Friedman MG, Hammerschlag MR. Infection with Simkania negevensis in Brooklyn, New York. Pediatr Infect Dis J 24:989-992, 2005. Apfalter P, Reischl U, Hammerschlag MR. In-house nucleic acid amplification assays in research: How much quality control is need before one can rely upon the results? J Clin Microbiol 43:5385-5841, 2005 Sleiman J. Hammerschlag, MR. ESBL-producing Gram-negative bacteria: A new threat to the community? Infect Med 23:0177-178, 2006. Hammerschlag MR, Gaydos GA. Chlamydia pneumoniae and multiple sclerosis: fact or fiction. Lancet Neurol 5:892-893, 2006. Kumar S, Kutlin A, Roblin P, Kohlhoff S, Bodetti T, Timms P, Hammerschlag MR. Isolation and antimicrobial susceptibilities of chlamydial isolates from western barred bandicoots. J Clin Microbiol 45:392-394, 2007. Kumar S, Hammerschlag MR. Acute respiratory infection due to Chlamydia pneumoniae: Current status of diagnostic methods. Clin Infect Dis 44:568-576, 2007. Sleiman JN, D’Angelo A, Hammerschlag MR. Spontaneous Escherichia coli cellulitis in a child with nephrotic syndrome. Pediatr Infect Dis J 26:266-267, 2007. Kumar S, Kohlhoff S, Sharma R, Valencia G, Hammerschlag MR. Treatment of vancomycin resistant Enterococcus faecium ventriculitis in a neonate. Int J Antimicrob Agents 29:740-741, 2007. Hammerschlag MR. Chlamydia and Chlamydiales: beyond Chlamydia trachomatis. Pediatr Infect Dis J, 26:639-639, 2007. D’Angelo A, Sleiman J, Mongia A. Schoeneman M, Hammerschlag M. Peritonitis caused by Neisseria sicca in a child on chronic peritoneal dialysis. Dialysis Transplant, in press, 2007. Kohlhoff SA, Kutlin A, Riska P, Roblin PM, Roman C, Hammerschlag MR. In vitro models of acute and long term continuous infection of human respiratory epithelial cells with Chlamydophila pneumoniae have opposing effects on host cell apoptosis. Microb Pathogen, in press, 2007. Rours GIJG, Hammerschlag MR, De Faber JTHN, de Groot R, Verkooyen RP. Chlamydia trachomatis as a cause of neonatal conjunctivitis Dutch infants. Pediatrics, in press, 2007. Bowser CS, Kumar S, Salciccioli, L, Kutlin A, Lazar J, Rahim I, Suss A, Kohlhoff, S, Hammerschlag MR, Moallem J. Absence of Chlamydia pneumoniae and signs of atherosclerotic cardiovascular disease in adolescents with systemic lupus erythematosus. Pediatr Cardiol, in press, 2007 Chapters Hammerschlag MR. Conjunctivitis in a 10-day old girl. In: Burg FD, Vaughan VC, Nelson KC (eds). Pediatrics: A Problem-Based Review. W.B. Saunders, Philadelphia, pp.91-93, 2000. Hammerschlag MR. Headache, nonproductive cough and fever in a 15 year-old boy. In: Burg FD, Vaughan VC, Nelson KC (eds) Pediatrics: A Problem-Based Review. W.B. Saunders, Philadelphia, pp.553-5, 2000. Hammerschlag MR. Chlamydia pneumoniae and asthma and atherosclerosis: Role of macrolides. In: Schönfeld W, Kirst H (eds). Milestones in Drug Therapy: Macrolide Antibiotics. Birkhauser Publishers Ltd, Basel, Switzerland, pp. 215-228, 2002. Hammerschlag MR. Syphilis. In: Burg FD, Inglefinger JR, Polin RA, Gershon AA (eds): Current Pediatric Therapy, 17th Edition. W.B. Saunders, Philadelphia, pp.102-104, 2002. Hammerschlag MR. Antibiotic susceptibility and treatment of Chlamydia pneumoniae infections. In: Yamamoto T, Freidman H, Bendinelli M (eds): Chlamydia pneumoniae Infection and Diseases. Kluwer Academic/Plenum Publishers, New York, in press, 2003. Hammerschlag MR. Chlamydia trachomatis. In: Hutto C (ed): Congenital and Perinatal Infections. A Concise Guide to Diagnosis. Humana Press, Totowa, NJ, pp. 261-269, 2005. Hammerschlag MR. Chlamydia Infections. In: Burg FD, Inglefinger JR, Polin RA, Gershon AA (eds): Current Pediatric Therapy, 18th ed. W.B. Saunders, Philadelphia, pp. 839-841, 2006. Kohlhoff S, Hammerschlag MR. Gonococcal and chlamydial infections in infants and children. In: Holmes KK, Sparling PF, Stamm WE, Piot P, Wasserheit JN, Cory L, Cohen M, Watts H (eds): Sexually Transmitted Diseases, 4th Ed, in press, 2007. Hammerschlag MR, Kumar S. Chlamydia infections. In: Taussig LM, Landau LI (eds): Pediatric Respiratory Medicine, 2nd Ed, in press, 2007. Hammerschlag MR. Chlamydia pneumoniae. In: Schlossberg D (ed): Clinical Infectious Diseases, 3rd Ed, in press, 2007. Sleiman J, Hammerschlag MR. Conjunctivitis. In: Shah S (ed): Pediatric Practice: Infectious Diseases, in press, 2007. Hammerschlag MR, Sleiman J. Neonatal conjunctivitis. In: Shah S (ed): Pediatric Practice: Infectious Diseases, in press, 2007.
MacMillan C, Magdar LS, Brouwers P, Chase C, Hittleman J, Lasky T, Malee K, Mellins CA, & Velez-Borras J, Women and Infants Transmission Study. Heads Growth and neurodevelopment of infants born to HIV-1 infected drug using women. Neurology, 2001, 57:1402-1410. Mellons C, Smith R, O’Driscoll P, Magder L, Brouwers P, Chase C, Blasini I, Hittleman J, Llorente A, Matzen E, Women and Infants Transmission Study Group. High rates of behavioral problems in Perinatally HIV infected children are not linked to HIV disease. Pediatrics, 2003, 111(2):384-393. Llorente A, Brouwers P, Charurat M, Magder L, Malee K, Mellins C, Ware J, Hittleman J, Mofenson l, Velez-Borras J, Adeniyi-Jones S, Women and Infants Transmission Study. Early neurodevelopmental markers predictive of mortality in infants infected with HIV-1, Developmental Medicine & Child Neurology, 2003, 45:76-84. Smith R, Malee K, Leighty R, Bouwers P, Mellins C, Hittleman J, Chase C, Blasini I, Women and Infants Transmission Study Group Effects of Perinatal HIV infection and associated risk factors on cognitive development among young children. Pediatrics, 2006, 117:851-862. Supervising Psychologist, Joan Hittleman, National Institute of Child Health and Human Development. Women and Infants Transmission Study (WITS) Factors that Contribute to the Vertical Transmission of HIV Disease and the Natural History of HIV Infection in Women and their Newborn Infants. 9/01/05-8/31/06 Principal Investigator and supervision, Joan Hittleman, Early Intervention, Department of Health, Project to provide therapeutic services to infants, birth to 3, and evaluate the performance of the project. 9/1/93-6/30/07 Principal Investigator and supervision, Joan Hittleman, Special Education, Department of Education, Project to provide services to infants, birth to 3 and evaluate the performance of the project. 9/1/87-6/1/07
Co-Principal Investigator, Harris Huberman, NIH/NICHD, National Institute of Child Health and Human Development, “Promoting Early School Readiness in Primary Health Care”, 2005-2009 M Agin, HS Huberman, KS Lobach. Developmental delay in young children: identification and intervention City Health Information 20(3):1-8, 2001 Berkule SB, Dreyer BP, Huberman HS, Fierman AH, Mendelsohn AL. Attitudes About Shared Reading Among At-Risk Mothers of Newborn Babies. Ambulatory Pediatrics. 7(1), 45-50, 2007. Project Director, Harris Huberman, NIH/NICHD, A low-intensity intervention to reduce delay, 3/15-02-2/28/06.
Bowser CS, Kaye J, Joks R, Charlot CA, Moallem HJ: IgE and atopy in perinatally HIV infected children, Pediatr Allergy Immunol 2007 Margaret Clark Golden Video: approach to the Pediatric Exam, Exam of the Newborn, and Exam of the Toddler in Swartz, Mark, Textbook of Physical Diagnosis, 5th Edition. Saunders PA 2006. Margaret Clark Golden & Ella Jean Richards, Video: The Adolescent Interview: Swartz, Mark, Textbook of Physical Diagnosis , 5th Edition, Saunders PA 2006.
Kaistha, A., Deckelbaum,. R.J, Starc, T.J, Couch, S.C. Over-restriction of dietary fat intake before formal nutritional counseling in children with hyperlipidemia. Arc pediatr Adolesc Med. 2001;55:1225-1230 Alfie, M. E., Iqbal, J., Kaistha, A., Fisher, .E., Hussain, M. (2005) Liver microsomal triglyceride transfer protein in a rat model of nonalcoholic fatty liver. J. Pediatr. Gastroenterol. Nutr. 41(4):522. Nanton, S., Iqbal, J., Anwar, K., Gupta, K., Shahanavaz, S., Kaistha, A., Hussain, M. and Wershil, B.K. (2005) Modulation of plasma cholesterol by mast cells. Am. J. Gasteroenterol. 100(s9):s371-s383. Pasternak B, Kaistha A: An unusual case of Anemia in an adolescent: Jejunal Adenocarcinoma: a rare cause of chronic anemia in children. JPGN-42:100-103 Jan 2006
Kolhoff S, Hammerschlag MR, Racoon Roundworm (Baylisascaris procyonis),Infect Med 2003;20(5):218-23 Kohlhoff S, Roblin P, Resnik T, Hawser S, Islam K, Hammerschlag MR, In vitro activity of a novel diaminopyrimide compound, iclaprim, against Chlamydia trachomatis and C. pneumoniae. Antimicrob Agents Chemother 2004;48(5):1885-6. Kohlhoff S, Marciano T, Rawstron S. Low-dose acyclovir for HSV-2 meningitis in a child. Acta Paediatr 2004;93(8)1123-4. Kutlin A, Kohlhoff S, Roblin P, Hammerschlag MR, Riska P. Emergence of resistance to rifampin and rifalazil in Chlamydophila pneumoniae and Chlamydia trachomatis. Antimicrob Agents Chemother March 2005;49(3): 903-7. Kumar S, Kohlhoff S, Gelling M, Roblin PM, Kutlin A, Kahane S, Friedman MG, Hammerschlag MR. The role of Simkania negevensis in respiratory disease in children in Brooklyn. Pediatr Infect Dis J 2005;24:989-92. Kumar S, Kohlhoff S. Recurrent HSV-2 meningitis in a 9 year old girl. Scand J Infect Dis 2006;38:570-2. Kumar S, Kohlhoff S, Gelling M, Roblin PM, Kutlin A, Kahane S, Friedman MG, Hammerschlag MR. Sinkania negenvensis is a rare but real pneumonia in children (reply to Don el. Al). Pediatric Infect Dis J 2006;25:471-2. Kohlhoff S, Kohler E, Sollich S. Serum myeloperoxidase in cystic fibrosis patients receiving systemic antibiotics. Scand J Infect Dis 2007;39:163-6. Kutlin A, Roblin P, Kumar S, Kohlhoff S, Bodetti T, Timms P, Hammerschlag MR. Molecular characterization of Chlamydophila pneumoniae isolates from Western Barred Bandicoots. J. Med Microbiol 2007;56-407-17. Kumar S, Roblin P, Kutlin A, Kohlhoff S, Hammerschlag MR. Isolation and Antimicrobial Susceptibilities of Chlamydial Isolates from Western Barred Bandicoots. J Clin Microbiol 2007;45:3392-4. Kumar S, Kohlhoff S, Sharma R, Valencia G, Hammerschlag MR. Treatment of vancomycin resistant Enterococcus faecium ventriculitis in a neonate. Int J Anticrob Agents 2006 (in press). Book Chapters Kohlhoff SA and Hammerschlag MR. Chapter: “Gonococcal and Chlamydial Infections in Infants and Children.” In: Sexually Transmitted Diseases, 4th edition, McGraw Hill, edited by king Holmes, P. Frederick Sparling, Walter Stamm, Peter Piot, Judith Wasserheit, larry Corey, Myron Cohen and Heather Watts (in press) Principal Investigator; Kohlhoff S; New Researcher Award Program Grant; Thrasher Research Fund; The response to Chlamydia pneumoniae infection of peripheral blood mononuclear cells in children with allergic asthma; 2006-present. Prinicipal Investigator; Kohlhoff S and Joks R; Pilot project grant; SUNY Downstate College of Medicine Research Investment Initiative; Characterization of Chlamydophila pneumoniae induced IgE responses and the effect of antibiotics in peripheral blood mononuclear cells from allergic asthmatics; 2007-present. Publications: Kohlhoff S , Kutlin A, Riska P, Roblin P, Roman C, Hammerschlag MR. In vitro models of acute and long term continuous infection of human respiratory epithelial cells with Chlamydophila pneumoniae have opposing effects on host cell apoptosis. Microb Pathogen 2007 (in press) Bowser CS, Kumar S, Salciccioli L, Kutlin A, Lazar J, Rahim I, Suss A, Kohlhoff S , Hammerschlag MR, Moallem J. Absence of Chlamydia pneumoniae and signs of atherosclerotic cardiovascular disease in adolescents with systemic lupus erythematosus. Pediatr Cardiol 2007 (in press). Kohlhoff S and Sharma R. Iclaprim. Expert Opin Investig Drugs 2007;16:1441-
Vaysman D, Davis JM, Rosenfeld W, Pollack S, Pucch P, Lee HS: Respiratory morbidity and pulmonary function in 5-6 year old children born prematurely and treated with recombinant human CuZn superoxide dismutase (Internet J of Pediatrics and Neonatology – in press) Veloira WG, Vaysman D, Lee HS: Acute respiratory failure secondary to primary spontaneous pneumothorax. Pediatric Emergency care 22:116-117, 2006. Vaysman D, Veloira WG, Schuss AL, Lee HS: Idiopathic Pulmonary Hemosiderosis. Pediatric Asthma, Allergy and Immunology 17:151-155, 2004. Mazzie JP, Price AP, Khullar P, Montoya CH, Roberts JE, Lee HS, Williams L, Schuss A, Katz DS: Radiology-Pathology Conference: Lymphomatoid Granulomatosis in a Pediatric Patient. Clinical Imaging 28:209-213, 2004. Article: 2006-2009 Lee HS: A Phase lllb Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Xolair in Subjects With Moderate To Severe Persistent Asthma Who are Inadequately Controlled With High-Dose Inhaled Corticosteroids and Long-Acting Beta-Agonists. Genentech, Inc. $ 9319/patient (co-investigator) 2005-2006 Lee HS: A Pivotal Phase 3 Study of MEDI-524 (NUMAX TM), an Enhanced Potency Humanized Respiratory Syncytial Virus (RSV) Monoclonal Antibody, for the Prophylaxis of Serious RSV Disease in High-Risk Children. Protocol MI-CP 110. Medimmune. $ 108, 450 2005-2006 Lee HS: A Randomized, 2- Period, Multicenter, Double-Blind, Parallel-Group Study Comaparing the Effects of 2 Doses of Montelukast Granules and Placebo in the Treatment of Respiratory Symptoms Associated with Respiratory Syncytial Virus-Induced Bronchiolitis in Children Aged 3 to 24 Months MK-0476 IND 58,819 Protocol 272-05. Merck $ 15,102 2004 Lee HS: Unrestricted educational grant. Genentech. $15,000 2003-2004 Lee HS: Twelve-Week, Randomized, Double-Blind, Double-Dummy, Active-Controlled Study of SYMBICORT pMDI Administered Once Daily in Children and Adolescents 6 to 15 years of Age with Asthma – SPROUT. AstraZeneca. $5,825 2003-2004 Lee HS: A Randomized, Double-Blind, Double- Dummy, Placebo- Controlled, Parallel Group, Multi-Center Clinical Trial of Four Weeks Treatment with SEREVENT Inhalation Aerosol, 25mcg BID, 50mcgBID and Placebo Administered Via a Valved Holding Chamber with Facemask in Subjects with Asthma Age 6 to 23 Months. GlaxoSmithKline. $2,000
Pediatric HIV/AIDS Cohort Study, (PHACS), SMAART Protocol, Hermann A. Mendez, Investigator. NIH/Harvard School of Public Health/WESTAT. Peer reviewed, August 1 2006-July 31,2008. Strug David, Ottman Ruth, Kaye Jackie, Saltzberg Shery, Walker Josephine, Mendez Hermann. Client Satisfaction and Staff Empathy at Pediatric HIV Programs. Journal of Social Service Research 2003; 29:1-22 Krogstad P, Lee S, Johnson G, Stanley K, McNamara J, Moye J, Jackson JB, Aguayo R, Dieudonne A, Khoury M, Mendez H, Nacjman S, Wiznia A; Pediatric AIDS Clinical Trials Group 377 Study Team. Nucleoside-analog reverse-transcriptease inhibitors plus nevirapine, nelfinair, or ritonavir for pretreated children infected with human immunodeficiency virus type 1. Clin Infect Dis. 34:991-100,2002 Das B, Posada R, Mendez H. Primary HIV Infection in an Adolescent presenting as Aseptic Meningitis. Indian J Pediatr 2002; 69:731.
Valdez-Faller TM, Mercado AB, Mercado-Asis LB. Response of Filipino patients with polycystic ovary disease to insulin sensitizer Rosiglitazone. Poster Presentation, Program and Abstracts, 31st Annual Convention, Philippine College of Physicians, May 10, 2001 and Poster, Program and Abstracts, 83rd Annual Meeting of the Endocrine Society, Denver, Colorado, June 2001 and 11th Congress of the ASEAN Federation of Endocrine Societies, Bali, Indonesia, November 7-11, 2001. Valdez-Faller TM, Mercado AB, Mercado-Asis LB. Lipid profile of Filipino patients with polycystic ovary disease. Poster Presentation, Program and Abstracts, 31st Annual Convention, Philippine College of Physicians, May 10, 2001 and Poster, Program and Abstracts, 83rd Annual Meeting of the Endocrine Society, Denver, Colorado, June 2001 and 11th Congress of the ASEAN Federation of Endocrine Societies, Bali, Indonesia, November 7-11, 2001. Mercado-Asis LB, Valdez-Faller TM, Mercado AB. Long term follow-up of Filipino patients with polycystic ovary syndrome (PCOS) with insulin sensitizer: From Troglitazone to Rosiglitazone. Poster Presentation, Program and Abstracts, 84th Annual Meeting of the Endocrine Society, San Francisco, California, June 19-22, 2002. Mercado-Asis LB, Mercado AB. Rosiglitazone is safe and effective in the treatment of insulin resistance in children and young adults. Poster Presentation, Program and Abstracts, 84thAnnual Meeting of the Endocrine Society, San Francisco, California, June 19-22, 2002. Mercado AB, Batista D, Keil MF, Jacobson J, Stratakis CA. Tall Stature in an Adolescent Male: An endocrine-Genetic Evaluation. Poster Presentation, Program and Abstract, 85th Annual Meeting of the endocrine Society, Philadelphia, PA, June 19-22, 2003. Faden D, Tanofsky-Kraff M, McDuffie J, Fredricks A, Mercado AB, Janovski JA. Loss of control eating and dieting in treatment–seeking overweight adolescents. Oral Presentation, Program and Abstracts, AED 2004 International Conference on Eating Disorders, Orlando, FL, Aril 29- May 3, 2004. Robotham D, Schoeller D, Mercado AB, Yanovski JA. Body fat in children is underestimated by the QDR4500 DXA relative to deuterium dilution. Poster Presentation, Program and Abstract, 2004 Pediatric Academic Societies’ Annual Meeting, San Francisco, CA, May 1-4-2004. Mercado AB, Shawker TH, Faden D, Fredricks A, Norman AC, Yanovski JA. Uterine and ovarian size are positively associated with body adiposity in overweight girls age 6-12y. Poster Presentation, Program and Abstract, Research Summaries Book (Selected from over 2,500 abstract and included in 125 newsworthy abstracts). 86th Annual Meeting of the Endocrine Society, New Orleans, LA, June 15-19, 2004. Norman AC, Drinkard B, McDuffie J, Ghorbani S, Mercado AB, Semega –Janneh M, Freedman, R, Janovski JA. Influence of body composition on exercise fitness and performance in overweight (OW) adolescents. Poster Presentation, Program and Abstracts, North American Association for the Study of Obesity’s 2004 Annual Scientific Meeting. Umpaichitra V, Mercado AB, Juan C, Quintos JB, Castells S. Adiponectin responses to Oral Glucose Tolerance Tests in adolescents with morbid obesity. Poster Presentation, Program and Abstract, 2006 Pediatric Academic Societies’ Annual Meeting, San Francisco, CA, April 29- May 2, 2006 and Oral Presentation, Program and Abstract, Eastern SPR Annual Meeting, March 18, 2006. Mercado AB, Umpaichitra V, Quintos JB, Castells S. Insulin, C-peptide and glucose load during 2-hour Oral Glucose Tolerance Test (OGTT) in morbidly obese adolescents. Poster Presentation, Program and Abstract, 2006 Pediatric Academic Societies’ Meeting, San Francisco, CA, April 29- May 2, 2006. Mercado AB, Wilson RC, Obeid J, New MI. Prenatal Diagnosis and Treatment of Congenital Adrenal Hyperplasia (21-Hydroxylase Deficiency): When the Parent is a Patient. 88th Annual Meeting of the Endocrine Society, Boston, MA, June 24-27, 2006. Mercado AB, Umpaichitra V, Quintos JB, Castells S. Association of adiponectin, insulin resistance and C-peptide in adolescents with morbid obesity. 88th Annual Meeting of the Endocrine Society, Boston, MA, June 24-27, 2006. Mercado AB, Quintos JB, Castells S. Insulin sensitivity indeces and lipid profile of morbidly obese adolescents. 88th Annual Meeting of the Endocrine Society, Boston, MA, June 24-27, 2006. Mercado-Asis LB, Mercado AB. Lipid Profile of Filipino Patients with Polycystic Ovary Disease (PCOS), J ASEAN Federation Endocrine Soc. 20:1 (Supp) 74 Jan 2002. Valdez-Faller, TM, Mercado AB, Mercado-Asis LB. Response of Filipino Patients with Polycystic Ovary Disease (PCOS) to Insulin Sensitizer Rosiglitazone. J ASEAN Fed Endo Soc 20:1 (Supp) 74 Jan 2002. Robotham D, Schoeller D, Mercado AB, Mirch MC, Theim KR, Reynolds JC, Yanovski JA. Estimated of body fat in children by Hologic QDR-2000 and QDR-4500 Dual-Energy X-ray Absorptiometers compared with deuterium dilution. J Pediatr Gastroenterol Nutr. 2006 Mar;42(3):331-335. Mercado AB, Castells S. Pancreatic b-Cell Hyperactivity in Morbidly Obese Adolescents. Pediatric Endocrinology Reviews. 2006 Dec;3(4):560-563. Quintos JB, Muzumdar H, George M, Mercado AB, Lu H, Sternberg A, Rao M, Castells S. The Prevalence of Metabolic Syndrome in Inner City Obese African-American Youth. Pediatric Endocrinology Reviews. 2006 Dec;3(4):571-575. Review, Chapters and Proceedings Mercado AB. Ambiguous genitalia. In: RM Perkin, JD Smith, DA Newton (eds.),Pediatric Hospital Medicine. In Textbook of Inpatient Management. Lippincott Williams and Wilkins, Philadelphia, PA, 2003, pp. 627-629.
Principal Investigator, Miller, ST, New York State Department of Health Expanded Comprehensive Sickle Cell Services Contract #C008267 Renewed July 1, 1999 - June 30, 2002
Principal Investigator (Local) Miller, ST Dept. of Health and Human Services, Maternal and Child Health Bureau MCHB 99-007 (Subcontract, New York State Dept. of Health) Improvement and Integration of Health Services within a State for Infants and Young Children with Sickle Cell Disease September 1,1999-May 31, 2002
Principal Investigator, Miller ST National Institutes of Health Pediatric Hydroxyurea Phase III Clinical Trial (BABY HUG)-Clinical Center Contract No. NO1-HB-07156 September 1,2000-December 31, 2009
Principal Investigator (Local) Miller ST Medical College of Georgia (subcontract) National Institutes of Health Optimizing Stroke Prevention In Children with Sickle Cell Disease (STOP2) Robert Adams, M.D., Principal Investigator NIH Contract #2 UO1-HL52193-06A1 MCG Subcontract MCG-STOP2-000967-16 July 1, 2000-June 30, 2004
Principal Investigator (Local) Miller ST Washington University, St. Louis (subcontract) WU-04-56 PO#29884B National Institutes of Health National Institute of Neurological Disorders and Stroke Contract U01-NS042804-01A1 Silent Infarct Transfusion Trial (SITT) Michael Debaun, MD, Principal Investigator September 30, 2003-June 30, 2010
Local Principal Investigator, Miller ST Quintiles, Inc. Icagen, Inc. ICA-17043-10 A Phase III, Multicenter, 52-Week, Randomized, Double-Blind, Placebo-Controlled Study of the Clinical Efficacy and Safety of ICA-17043 with or without Hydroxyurea Therapy in Patients with Sickle Cell Disease 4/14/05-4/07
Medical Consultant, Miller ST New England Research Inc. NIH/NHLBI 1 U1O HL083721-01 Sickle Cell Disease Clinical Research Network-Data Coordinating Center Donald Brambilla, Principal Investigator April 10, 2006-March 31, 2011
Local Principal Investigator St. Jude Children's Research Hospital NIH/NHLBI Principal Investigator Russell Ware MD PhD 1U01 HL078787-01A1 Stroke with Tranfusions Changing to Hydroxyurea (SWITCH) October 2005-July 31, 2007 Renewal Pending
Miller ST, Sleeper LA, Pegelow CH, Enos LE, Wang WC, Weiner SJ, Wethers DL, Smith J, Kinney TR. Predicting adverse outcomes in children with sickle cell disease: a report from the Cooperative Study (CSSCD). N Engl J Med 2000;342:83-9. Sakhalkar VS, Rao SP, Gottessman SRS, Miller ST. Hemophagocytosis and granulomas in a child with Down syndrome. J Pediatr Hematol/Oncol 2001;23:623-5. Miller ST, Wright E, Abboud M, Berman B, Files B, Scher CD, Styles L, Adams RJ. Impact of chronic transfusion on incidence of pain and acute chest syndrome during the Stroke Prevention Trial (STOP) in sickle cell anemia. J Pediatr 2001;139:785-9. Miller ST, Macklin EA, Pegelow CH, Kinney TR, Sleeper LA, Bello JA, DeWitt D, Gallagher DM, Guarini L, Moser FG, Ohene-Frempong K, Sanchez N, Vichinsky EP, Wang WC, Wethers DL, Younkin DP, Zimmerman RA, DeBaun MR. "Silent infarction" as a risk factor for overt stroke in children with sickle cell disease: a report from the Cooperative Study (CSSCD). J Pediatr 2001;139:385-90. Files B, Brambilla D, Kutlar A, Miller S, Vichinsky E, Wang W, Granger S, Adams RJ. Longitudinal changes in ferritin during chronic transfusion: A report from the Stroke Prevention Trial in Sickle Cell Anemia (STOP). J Pediatr Hematol/Oncol 2002;24:284-90. Pegelow CH, Macklin EA, Moser FG, Wang WC, Bello JA, Miller ST, Vichinsky EP, DeBaun MR, Guarini L, Zimmerman RA, Younkin DP, Gallagher DM, Kinney TR. Longitudinal changes in brain MRI findings in children with sickle cell disease. Blood 2002;99:3014-3018. Miller ST, Wright E, Brambilla D, Adams RJ. Stroke prevention trial in sickle cell anemia: Comments on effects of chronic transfusion on pain-Reply (letter). J Pediatr 2002;141:743. Saxena VR, Mina R, Moallem HJ, Rao SP, Miller ST. Systemic lupus erythematosus in children with sickle cell disease. Amer J Pediatr Hematol/Oncol 2003;25:668-71. Hsu LL, Miller ST, Wright E, Kutlar A, McKie V, Wang W, Pegelow CH, Driscoll C, Hurlet A, Woods G, Elsas L, Embury S, Adams RJ. Alpha thalassemia is associated with decreased risk of abnormal transcranial Doppler ultrasonography in children with sickle cell anemia. J Pediatr Hematol/Oncol 2003;25:622-8. Miller ST, Rao SP. Acute chest syndrome, transfusion, and neurological events in children with sickle cell disease (letter). Blood 2003;102:1556. Reid ME, Storry JR, Sausais L, Tossas E, Rios M, Hue-Roye K, Gloster ES, Miller ST, Wolf C, Lomas-Francis C. DAK, a new low-incidence antigen in the Rh blood group system. Transfusion. 2003;43(10):1394-7. Adamkiewicz TV, Sarnaik S, Buchanan GR, Iyer RV, Miller ST, Pegelow CH, Rogers ZR, Vichinsky E, Elliot J, Facklam RR, O'Brien KL, Schwartz B, Van Beneden CA, Cannon MJ, Eckman JR, Keyserling H, Sullivan K, Wong W, Wang WC. Invasive pneumococcal infections in children with sickle cell disease in the era of penicillin prophylaxis and antibiotic resistance. J Pediatr 2003;143:438-44. Goyal M, Miller ST, Hammerschlag MR, Gelling M, Gaydos CA, Wood BJ, Reznik T, Rao SP. Stroke in children with sickle cell disease: Lack of association with Chlamydia pneumoniae infection. Pediatrics 2004;113:e318-e321. Sakhalkar VS, Rao SP, Weedon J, Miller ST. Elevated plasma sVCAM-1 levels in children with sickle cell disease: impact of chronic transfusion therapy. The Optimizing Stroke Prevention in Sickle Cell Anemia (STOP 2) Trial Investigators. Discontinuing prophylactic transfusion to prevent stroke in sickle cell disease. N Engl J Med 2005;353:25-34. (Acknowledged as Investigator, Miller ST, and member of Manuscript Preparation Committee) Lee MT, Piomelli S, Granger S, Miller ST, Harkness S, Brambilla DJ, Adams RJ. Stroke Prevention trial in sickle Cell Anemia (STOP): extended follow-up and final results. Blood 2006;108:847-52. Seeyave D, Desai N, Miller S, Rao SP, Piecuch S. Delayed hemolytic transfusion reaction with hyperhemolysis syndrome and sepsis in a patient with sickle cell anemia. J National Med Assoc 2006 Oct;98:1697-9. Kwiatkowski JL, Granger S, Brambilla DJ, Brown RC, Miller ST, Adams RJ. Elevated blood flow velocity in the anterior cerebral artery and stroke risk in sickle cell disease: extended analysis from the STOP trial. Brit J Hematol 2006;134:333-9. Brambilla DG, Miller ST, Adams RJ for the STOP and STOP 2 Investigative Teams. Intra-individual variation in blood flow velocities detected by transcranial Doppler ultrasonography in children with sickle cell disease. Pediatr Blood Cancer 2007 Jan 22 (Epub ahead of print). INVITED ARTICLES Quinn C, Miller ST. Risk factors and prediction of outcomes in children and adolescents who have sickle cell anemia. Hematol Oncol Clin N Amer 2004;18(6):1339-54. CHAPTERS Miller ST. Sickle Cell Disease. In Saunders Manual of Pediatric Practice. Finberg L, ed., W.B. Saunders Co., Philadelphia Pa., 1998, pp 407-13. Edition 2, 2002, pp 472-9. Miller ST. Thalassemias. In Saunders Manual of Pediatric Practice. Finberg L, ed., W.B. Saunders Co., Philadelphia Pa., 1998, pp 413-17. Edition 2, 2002, pp 479-84. Miller ST. Sickle cell anemia with fever. In Atlas of Pediatric Emergency Medicine. Shah BR and Lucchesi M, eds. The McGraw-Hill Companies, New York, NY, 2006, pp 463-5. Miller ST. Sickle cell anemia with acute pain episode. In Atlas of Pediatric Emergency Medicine. Shah BR and Lucchesi M, eds. The McGraw-Hill Companies, New York, NY, 2006, pp 466-8. Miller ST. Sickle cell anemia with acute chest syndrome. In Atlas of Pediatric Emergency Medicine. Shah BR and Lucchesi M, eds. The McGraw-Hill Companies, New York, NY, 2006, pp 469-70. Miller ST. Sickle cell anemia with priapism. In Atlas of Pediatric Emergency Medicine. Shah BR and Lucchesi M, eds. The McGraw-Hill Companies, New York, NY, 2006, pp 471-3. Miller ST. Sickle cell anemia with cerebrovascular disease. In Atlas of Pediatric Emergency Medicine. Shah BR and Lucchesi M, eds. The McGraw-Hill Companies, New York, NY, 2006, pp 474-6. CONTRIBUTOR Guidelines for the Treatment of People with Sickle Cell Disease. The Sickle Cell Advisory Committee of the Genetic Network of New York, Puerto Rico and the Virgin Islands, New York State Department of Health, March 2002. (http://www.scinfo.org/SCACguide.rtf)
Principal Investigator, Jack Hamid Moallem, NICHD (WESTAT) “Pediatric AIDS Clinical Trial Group”, 2001-6 Bowser CS, Kaye J, Leier TU, Chorney V, Nathawad R, Chernichenko, N, Shin A, Pragaspathy B, Moallem J: Prevalence of viral and Mycobacterial co-infections in perinatally HIV – infected children, Fetal nd Pediatric pathology 25(6)2006 Bowser CS, Kaye J, Joks R, Charlot CA, Moallem HJ: IgE and atopy in perinatally HIV infected children, Pediatr Allergy Immunol 2007 Bowser CS, Kaye J, Chrnichenko N, Nathawad R, Shin A, Pragaspathy B, Moallem HJ: Prevalance of Infection with herpes simplex (HSV) 1 & 11 in children with perinatally Acquired HIV infection. World Congress of Allergy & Immunology, Munich, June 2005 Perenyi A Effect of maternal antibiotic treatment on neonatal sepsis -principal investigator Perenyi A, 2002-2006 Shorter NA, Georges A, Perenyi A, Garrow E. A proposed classification system for familial intestinal atresia and its relevance to the understanding of the etiology of jejunoileal atresia, Journal of Pediatric Surgery, 41/11, 1822-25,2006 Sherer DM, Perenyi A, Glick S, Dalloul M, Zigalo A, Gupta R, Abulafia O, Prenatal sonographic findings of extensive low-flow mixed lymphatic and venous malformations, Ultrasound Med. 25:1469-73, 2006. Goldstein NA, Pugazhendhi V, Rao M, Weedon J, Campbell TF, Goldman AC, Post JC, Rao M. Clinical assessment of pediatric obstructive sleep apnea. Pediatrics, 2004 Jul;114(1):33-43. Sternberg A, Murphy C, Austin-Leon G, Rao M, Application of shotokan karate exercises in an obese inner-city pediatric population who participated in the Downstart healthy lifestyle program. Med Sci Sports Exerc. 2007 May:39(5Suppl):S387. Sternberg A, Muzumdar H, Dinkevich E, Quintos JB, Austin-Leon G, Owens T. Murphy C, Dapul G, Rao M. The Downstart program: a hospital-based pediatric healthy lifestyle program for obese and morbidly obese minority youth. Pediatr Endocrinol Rev. 2006 Dec;3 Suppl 4:584-9. Quintos JB, Muzumdar H, George M, Mercado AB, Lu H, Sternberg A, Rao M, Castells S. The prevalence of metabolic syndrome in inner city obese African-American youth. Pediatr Endocrinol Rev. 2006 Dec;3 Suppl 4:571-5. Principal Investigator, SP Rao, Children's Cancer Study Group Studies at Downstate Medical Center 1978 to present Sakhalkar VS, Rao SP, Gottesman SRS, Miller ST. Hemophagocytosis and Granulomas in the Bone Marrow of a Child with Down Syndrome. J Pediatr Hematol/Oncol 2001; 23:623-5 Mathur M, Sykes JA, Saxena VR, Rao SP and Goldman GM: Treatment of Acute Lymphoblastic Leukemia Induced Extreme Hypercalcemia with Pamidronate and Calcitonin. Pediatric Critical Care Medicine,2003;4(2):252-255 Gustavsson P, Klar J, Mattson H, Forestir E, Henter J, Rao SP, Seip M, Skeppner G and Dahl N: Familial transient erythroblastopenia of childhood is associated with the chromosome 19q13.2 region but not caused by mutations in coding sequences of the ribosomal proteins19 (RPS19) gene. British Journal of Hematology 2002; 119, 261-264 Saxena V, Mina R, Moallem H, Rao SP, and Miller S: Systemic Lupus Erythematosus in Children with Sickle Cell Disease. J Pediatr Hematol/Oncol 2003; 25:668-671 Sakhalkar V, Rao SP, Weeden J and Miller S: Elevated Plasma sVCAM-1 Levels in Children with Sickle Cell Disease: Impact of Chronic Transfusion Therapy. Amer J Hematol 2004; 76:57-60 Miller ST, Rao SP: Acute chest syndrome, transfusion and neurological events in children with sickle cell disease (letter) Blood 2003;102:1556 Goyal M, Miller ST, Hammerschlag MR, Gelling M, Gaydos CA, Wood BJ, Reznik T, Rao SP: Stroke in children with sickle cell diseae: Lack of association with Chlamydia Pneumoniae infection. Pediatrics 2004; 113:e318-321 Yassin y, Rothenberg S, Rao SP, Gordon M, Alpers DH, Quadros EV: Identification of 4-base deletion in the gene in inherited intrinsic factor deficiency. Blood 2004; 103:1515-1517 Mathur M, Desai N, Sharma J, Rao SP: Management of a large intra-trial catheter-tip thrombus in a child with TPA infusions. Pediatric Critical Care Medicine.2005; 6:79-82 Khoa D, Koprowska I, Rao SP, Sundaram R and Goldstein N: Myringotomy and tympanostomy tube placement in children with sickle cell disease. International Journal of Pediatric Otorhinolaryngology 2004; 68(10):1301-1305 Seeyave D, Desai N, Miller s, Rao SP, Piecuch S. Delayed hemolytic transfusion reaction with hyperhemolysis syndrome and sepsis in a patient with sickle cell anemia. J National Med Assoc (in press) Chapters Rao SP:Acute immune thrombocytopenic purpura. In Atlas of Pediatric Emergency Medicine. Shah BR, Lucchesi M, eds. The Mcgraw Hill Companies, New York, NY, 2006,477-79. Rao SP: Hemophilia.In Atlas of Pediatric Emergency Medicine. Shah BR, Lucchesi M, eds. The Mcgraw Hill Companies, New York, NY, 2006,480-482 Rao SP: Abdominal Mass.in Atlas of Pediatric Emergency Medicine. Shah BR, Lucchesi M, eds. The Mcgraw Hill Companies, New York, NY, 2006, 480-86 Rao SP: Lymphadenopathy. In Atlas of Pediatric Emergency Medicine. Shah BR, Lucchesi M, eds. The Mcgraw Hill Companies, New York, NY, 2006,487-490
Richards, Ella Jean, Video: The Adolescent Interview: Swartz, Mark, Textbook of Physical Diagnosis, 5th Edition, Saunders PA 2006. Sternberg A, Murphy C, Austin-Leon G, Rao M, Application of shotokan karate exercises in an obese inner-city pediatric population who participated in the Downstart healthy lifestyle program. Med Sci Sports Exerc. 2007 May:39(5Suppl):S387. Sternberg A, Muzumdar H, Dinkevich E, Quintos JB, Austin-Leon G, Owens T. Murphy C, Dapul G, Rao M. The Downstart program: a hospital-based pediatric healthy lifestyle program for obese and morbidly obese minority youth. Pediatr Endocrinol Rev. 2006 Dec;3 Suppl 4:584-9. Quintos JB, Muzumdar H, George M, Mercado AB, Lu H, Sternberg A, Rao M, Castells S. The prevalence of metabolic syndrome in inner city obese African-American youth. Pediatr Endocrinol Rev. 2006 Dec;3 Suppl 4:571-5.
Schwarz SM, Corredor J, Fisher-Medina J, Cohen J and Rabinowitz S. Diagnosis and treatment of feeding disorders in children with developmental disabilities. Pediatrics 108: 671-676, 2001. Schwarz SM: Nutritional management of disabled patients – a new formula for success? Nutrition 18: 681-683, 2002. Rabinowitz SS, Piecuch S, Jibali R, Goldsmith A and Schwarz SM. Optimizing the diagnosis of gastroesophageal reflux in children with otolaryngologic symptoms. Int J Pediatr Otorhinolaryngol l67: 621-626, 2003. Schwarz SM. Feeding disorders in children with developmental disabilities. Infants and Young Children 16: 317-330, 2003. Crandall WV, Barnard JA, Cohen MB, Colletti RB, Ferry GD, Harnsberger JK, Hart MH, Hayes JR, Rosenthal P. Sherman PM, Smith LJ, Baron H, Blank E, Collins E, Marpavat M, Huffman S, Lewis J, McDuffie A, Montes R, Nelson S, Schwarz SM, Splawski J, Strople J and Weerasooiya V. Pediatric gastroentero-logy workforce survey, 2003-2004: A report of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr 40: 397-405, 2005. Ton M, Suwandhi E and Schwarz SM. Gastroesophageal reflux. Pediatr Ann 35: 259-266, 2006. Schwarz SM, Lightdale J and Liacouras C. Sedation and analgesia in pediatric endoscopy: The search for a standard of care. . J Pediatr Gastroenterol Nutr 3: 295-297, 2007. Schwarz SM: Management of feeding disorders in children with developmental disabilities. In David TJ, editor, Recent Advances in Pediatrics 20. London, UK, The Royal Society of Medicine Press, Ltd., 99-113, 2002. Schwarz SM. Biliary atresia. In Althschuler S et al, editors, Pediatrics: An Online Medical Reference, 2nd Edition. St. Petersburg, FL, Emedicine Online Textbooks, 2005. Schwarz SM. Gastrointestinal complaints. Pediatr Ann 35: 232-235, 2006 Golden N., Seigel WM, Fisher M, Schneider M, Quijano E, Suss AL , Bergeson R, Seitz M, Saunders D. Emergency contraception: pediatricians’ knowledge, attitudes, and opinions. Pediatrics. 2001;107:287-292. Suss, A . Chapters: Gonorrhea, Herpes, Trichomoniasis, Dysfunctional Uterine Bleeding, Pelvic Inflammatory Disease, and Ectopic Pregnancy, In: Atlas of Pediatric Emergency Medicine: Shah BR and Lucchesi M (eds). McGraw-Hill Medical Publishing Division, USA, 2006; 180-196
Kukreja A, Costi G, Marker J, Zhang C, Sun Z, Lin-Su K, Ten S, Sanz M, Exley M, Wilson B, Porcelli, Maclaren N. Multipl4e immuno-regulatory defects in type-1 diabetes, J Clin Invest 2002; 109(1):131-140. Kukreja A, Costi G, Marker J, Zhang C, Sun Z, Lin-Su K, Ten S, Sanz M, Exley M, Wilson B, Porcelli, Maclaren N. Multiple immuno-regulatory defects in type-1 diabetes. J Clin Invest. 2002 Jan;109(1):131-40. Svetlana Ten MD, Anjli Kukreja PhD, Noel Mcclaren MD. Associations between immune-mediated (type1) diabetes and other autoimmune diseases, diabetes mellitus: a fundamental and Clinical test (Leroith and Olefsky, eds), Lippincott Williams & Wilkins, 2003. Svetlana Ten, Noel K Maclaren. Insulin resistance syndrome in children. Review, J Clin Endocrinol Metab 2004, 84:2526-2539. Svetlan Ten MD, Amrit Bhangoo MD, Neesha Ramchandi PNP, Charles Mueller PhD, Maria Vogiatzi MD, Maria New MD, Martin Lesser PhD, Noel Maclaren MD. Characterization of Insulin Resistance Syndrome in Children and Young Adults. When to Screen for Prediabetes? JPEM(in press) Svetlana Ten, Neesha Ramchandani, Amrit Bhangoo, Madelaine Harbison, Maria Vogiatzi, Maria New, Martin Lesser PhD, Noel Maclaren. Compensated isulin resistance is characterized by elevated acute insulin response and elevated REE JPEM (in press). Smotkin-Tangorra M, Radhika Purushothaman, Ashutosh Gupta, Golali Nejati, Henry Anhalt, Svetlna Ten, Prevalence of Vitamin D Insufficiency in Obese Children and Adolescents. JPEM (in press) Smotkin-Tangorra M, Anhalt, Ten S. King SR. Phenoyypic variations in lipoid congential adrenal hyperplasia. Pediatr Endocrinol Rev. 2006, mar;3(3):258-71. Radhika Purushothaman, Gupta A, Anhalt, Ten S. Hypothyroidism caused by chronic autoimmune thyroiditis in very young children: case report and review of literature. The Endocrinologist 206; (16) 5. Smotkin-Tangorra M, Anhalt H, Ten S. Growth hormone and premature atherosclerosis in childhood obesity. J Pediatr Endocrinol Metab. 2006 Apr;19(4):455-65.Review Ramchandani N, Ten S, Anhalt H, Sinha S, Ching J, Finkelstein A, Maclaren NK. Insulin pump therapy from the time of diagnosis of type 1 diabetes . Diabetes Technol Ther. 2006 Dec;8(6):663-70. Mullen RD, Colvin SC, Hunter CS, Savage JJ, Walvoord EC, Bhangoo AP, Ten A, Weigel J, Pfaffle RW, Rhodes SJ. Roles of the LHX3 and LHX4 LIM-homeodomain factors in pituitary development. Mol Cell Endocrinol. 2007 Jan 8. Gunturu SD, Ten S. Complications of obesity in childhood. Pediatr Ann. 2007 Feb;36(2):96-101. Motaghedi R, Gujral S, Sinha S, Sison C, Ten S, Maclaren NK. Insulin-like growth factor binding protein-1 to screen for insulin resistance in children. Diabetes Technol Ther. 2007 Feb;9(1):43-51. Mackey J, Treem WR, Worley G, et al. Frequency of celiac disease in individuals with Down syndrome in the United States. Clin Pediatr 2001;40:249-252. Orenstein SR, Blumer JL, Faessel HM, Pappa KA, McGuire JA, Furg K, Li B, Lavine JE, Treem WR, Ciociola AA. Ranitidine, 75 mg, over-the-counter dose: pharmacokinetic and pharmacodynamic effects in children with symptoms of gastro-esophageal reflux. Alimentary Pharmacology & Therapeutics, 16(5):899-907, May 2002. Treem WR. Mitochondrial fatty acid oxidation and acute fatty liver of pregnancy. Seminars in Gastrointestinal Dis, 2002;13:55-66. Kader HA, Berman WF, Al-Seraihy AS, Ware RE, Ulshen MH, Treem WR. Prevalence of factor V G1691A (Leiden), prothrombin G20210A, and methylenetetrahydrofolate reductase G677T thrombophilic mutations in children with inflammatory bowel disease. J Pediatr Gastroenterol Nutr, 2002;35:629-635. Ware RE, Zimmerman SA, Sylvestre PB, Davis JS, Treem WR, Schutz WH. Prevention of secondary stroke and resolution of transfusional iron overload in children with sickle cell anemia using hydroxyurea and phlebotomy. J Pediatr, 2004; 145:346-352. Treem WR. Emerging concepts in celiac disease. Current Opinion in Pediatrics, 2004;16:552-559. Hyams J, Markowitz J, Otley A, Rosh J, Mack D, Bousvaros A, Kugathasan S, Pfefferkorn M, Tolia V, Evans J, Treem WR, Wyllie R, rothbaum R, del Rosario J, Katz A, Mezoff A, Oliva-Hemker M, Lerer T, Griffiths A, for the Pediatric Inflammatory Bowel Disease Collaborative Research Group. Evaluation of the pediatric Crohn’s disease activity index: a prospective multi-center experience. J Pediatr Gastroenterol Nutr, 2005;41:416-421. Wang J, Cortina G, Wu V, Tran R, Cho JH, Tsai MJ, Bailey T, Jamrich M, Ament M, Treem WR, Hill I, Vargas J, Gershman G, Farmer D, Reyen L, Martin M. Homozygote mutations of Neurogenin-3 in children with congenital generalized malabsorptive diarrhea and dysgenesis of enteroendocrine cells. N Engl J Med 2006; 355: 270-280. Cortina G, Burge CN, Farmer D, Bhuta S, Treem WR, Hill I, Martin MG. Enteroendocrine cell dysgenesis and malabsorption, a histopathological and immunohistochemical characterization. Human Pathology 2007;38:570-580. Matern D, Hart P, Murtha AP, Vockley J, Gregersen N, Millington DS, Treem WR. Acute fatty liver of pregnancy associated with short-chain acyl-coenzyme A dehydrogenase deficiency. J Pediatrics, 2001;138:585-588. Hochman JA, Treem WR, Dougherty F, Bentley RC. Mucolipidosis II (I-Cell disease) presenting as neonatal cholestasis. J Inher Metab Dis, 2001;24:603-604. Rosoff PM, Tuttle-Newhall E, Treem WR Successful treatment of immune thrombocytopenic purpura with anti-D antibody following a cadaveric liver transplant for hepatoblastoma. Med Ped Oncol, 2003;40:402-404. Lazarre F, Nguyen K, Kaistha A, Treem WR. A previously undescribed CFTR mutation in a Hispanic infant presenting with meconium ileus and perforation. Submitted, J Cystic Fibrosis, 2007. Chogle A, Nguyen K, Lazare F, Guzman M, Anderson V, Treem WR. Gastric Burkitt’s Lymphoma: A rare cause of upper gastrointestinal bleeding in a child with HIV/AIDS. Submitted, J Pediatr Gastroenterol Nutr, 2007. Treem WR. Pediatric Biliary Diseases. Baillie J, Clavien P (eds.) Diseases of the Gallbladder and Bile Ducts: Diagnosis and Treatment. Blackwell Science, 2001;309-334. Treem WR. Assessing Crying Complaints: Interaction with Gastroesophageal Reflux and Cows Milk Protein Intolerance. In New Evidence on Unexplained Early Infant Crying: Its Origins, Nature, and Management. Johnson and Johnson Pediatric Round Table, 2001;165-176. Treem WR. Special Considerations for Liver Transplantation in Children. In Clavien PA, Killenberg (eds). Medical Care of the Liver Transplant Patient. Second Edition. Blackwell Scientific Publishers, London, 2001;393-432. Sokol R, Treem WR. Mitochondrial Hepatopathies. In Suchy F, Sokol R, Balistreri W (eds). Liver Disease in Children. Lippincott, Williams, Wilkins (2nd edition) Philadelphia, 2001; 787-801. Sokol RJ, Treem WR, Mitochondrial hepatopathies in infants and children: primary and secondary disorders (Hepatopatias Mitocondriais em Lactentes e em Criancas: Disturbios Primarios e Secundarios) In: da Costa Gayotto LC, Alves VAF (eds.). Diseases of the Liver and Biliary Tract, (Doencas do Figado e Vias Biliares), 2001; 335-347. Treem WR. Inborn Defects in Mitochondrial Fatty Acid Oxidation. In Suchy F, Sokal R, Balistreri W (eds). Liver Disease in Children. Lippincott, Williams, Wilkins (2nd edition) Philadelphia, 2001; 735-785. Kader HA, Berman WF, Al-Seraihy AS, Ware RE, Ulshen MH, Treem WR. Prevalence of Factor V (Leiden), Prothrombin G 20210A, and methylenetetrahydrofolate redctase C677T thrombophilic mutations in children with inflammatory bowel disease. J Pediatr Gastroenterol Nutr, 2001;33:371. Ware RE, Sylvestre PB, MacKeigan SF, T |
